图书简介
With contributions from leading international academics across the biological sciences, this handbook takes a critical look at the key contemporary issues and debates in the field. The 31 chapters are divided into four parts: Part I Determination of Substance Misuse Part II PK and PD in Relation to Patterns of Use Part III Detection and Treatment of Drug and Alcohol Use Part IV Controversies and New Approaches This Handbook is an excellent reference text for the growing number of academics, students, scientists and practitioners in the drug and alcohol studies community, and will be a vital resource to the allied professions involved in work-place drug testing, clinical toxicology, and forensic science.
Section One: Determination of Substance Misuse \\ 1. Genetics and genomics in addiction researchRohit Jaibhagwan Lodhi, David Rossolatos and Katherine Jean Aitchison \\ 2. Basic Pharmacokinetics of Substance MisuseKim Wolff \\ 3. Future Directions: The role of pharmacogenomics Jason White & Andrew Somogyi \\ Section Two: PK and PD in Relation to Patterns of Use \\ 4. Alcohol: Pharmacokinetics and Pharmacodynamics Matthew Goldin and E Jane Marshall \\ 5. Nicotine: The Pharmacokinetics of Nicotine and CotinineNoor Robson \\ 6. Emerging Tobacco Trends from the Arabian Cultures (Waterpipe and Dokha): Global Prevalence, Health Risks and Propensity for AbuseAnnie Crookes \\ 7. Opioids: A Discussion of Pharmacokinetics and Pharmacodynamics of Opioids in Those Who Misuse DrugsVerena Metz & Sandy Corner \\ 8. Cocaine: pharmacokinetics, pharmacodynamics and addictive potentialGlenn Dumont \\ 9. Amphetamine & Methamphetamine: Pharmacokinetics and PharmacodynamicsKim P.C. Kuypers, Eef Theunissen and Jan Ramaekers \\ 10. MDMA: PharmacokineticsMagí Farré, Esther Papaseit & Rafael de la Torre \\ 11. Benzodiazepines: A discussion of pharmacokinetic and pharmacodynamic effects in those who misuse the drug Alyson Bond & Malcolm Lader \\ 12. Ketamine: the pharmacokinetics and pharmacodynamics in medicinal and misusing populationsKim Wolff \\ 13. Cannabis: The pharmacokinetics and pharmacodynamics of recreational and medicinal cannabisDave Allsop, Richard Kevin & Jonathon Arnold \\ 14. Synthetic cannabinoids: The pharmacokinetics and pharmacodynamics of ‘Spice’ and other synthetic cannabinoids Deepak D’Souza & Aarti Gupta \\ 15. Khat, Methedrone and MDPV: A discussion of pharmacokinetic and pharmacodynamic parameters Lorenza Colzato & Manuel Ruiz \\ 16. Gamma-hydroxybutyric Acid (GHB): A discussion of pharmacokinetic and pharmacodynamic effects of GHB including its analogues John B. Saunders, Jason Connor & Gerald Feeney \\ 17. Polysubstance Use Jason Connor, John Saunders, Adrian Kelly, Gerald Feeney \\ Section Three: Detection and Treatment of Drug and Alcohol Use \\ 18. A brief overview of the detection of drug and alcohol use: the matching of purposes and procedures.Kim Wolff & Michael Gossop \\ 19. Biomarkers of drug useKim Wolff & Michael Gossop \\ 20. Biomarkers of alcohol useNatalie E Walsham & Roy A Sherwood \\ 21. Pharmacotherapy: What worksJohn Witton \\ 22. Treatment of Opioid DependenceKim Wolff, Steven Karch, Jason White \\ 23. Wastewater Analysis for the Measurement of Population Level Drug Use: Sewage-Based EpidemiologyBram Miserez & Alexander van Nujs \\ Section Four: Special Settings \\ 24. Forensic and postmortem toxicology A Robert Forrest \\ 25. The workplace: alcohol use disorders and convictions for alcohol-related offencesKim Wolff, Samantha Gross, Noor Zurani-Robson and Jane Marshall \\ 26. Future directions: What is the way forward for toxicology and forensic research?Steven B Karch \\ Section Five: Controversies and New Approaches \\ 27. Intravenous abuse of methylphenidateBjarni O. Rafnar and Gudrun Dora Bjarnadottir \\ 28. Non addictive drug use: The way forwardChristian P. Müller \\ 29. Different Approaches to setting limits for drugs and alcohol use when driving Kim Wolff \\ 30. Where do gambling and internet ‘addictions’ belong? The status of ‘other’ addictionsMark D. Griffiths, Daria J. Kuss, Halley M. Pontes and Joël Billieux \\ 31. The treatment of benzodiazepine dependence: Maintenance or abstinence?Deborah Zador \\ 32. ADHD: Pathway into Addiction, Option for Treatment?Pieter-Jan Carpentier, Philip Asherson & Ulrich Muller \\ 33. Attention Deficit Hyperactivity Disorder and its association with Substance UseSusan Young & Ottilie Sedgwick
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