Thalassemia is discussed comprehensively by the authors in this issue. Topics discussed include the population genetics and dynamimcs of thalassemia, alpha thalassemia, HbE/beta thalassemia, management of iron overload in thalassemia syndromes, allogeneic cellular gene therapy for hemoglobinopathies, cord blood transplantation for beta thalassemia major, and gene therapy for hemoglobin disorders.
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A recent Institute of Medicine report has concluded that "there is a lack of knowledge and awareness about chronic