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SECTION I: Movement Disorders (Joel Perlmutter, Washington University); 1. History of Parkinsonism; Michael Silver, MD and Stewart A. Factor, DO; 2. Parkinson Disease: Pathophysiology, Clinical Manifestations and Course including Diagnosis and Differential Diagnosis; Michael J. Soileau, MD and Kelvin L. Chou, MD; 3. Parkinson Disease: Treatment, Current Clinical Trials; Thien Thien Lim, MD and Hubert H. Fernandez, MD; 4. Parkinson Syndromes: Multiple System Atrophy; Melvin W. Kong, MD and Ejaz A. Shamim MD, MS; 5. Parkinson Syndromes: Progressive Supranuclear Palsy; Vikas Kotagal, MD, MS and Praveen Dayalu, MD; 6. Parkinson Syndromes: Corticobasal Degeneration; Sami Barmada, MD, PhD; 7. Huntington Disease: Etiology, Genetics, and Clinical Manifestations; Roger L. Albin, MD and Henry L. Paulson, MD, PhD; 8. Huntington Disease: Treatment, Current Clinical Trials; Charles S. Venuto, PharmD and Karl Kieburtz, MD, MPH; 9. Essential Tremors; Arif Dalvi, MD, MBA, Kelly E. Lyons, PhD, and Rajesh Pahwa, MD; 10. Dystonia: History and Classification; H. A. Jinnah, MD, Cecilia N. Prudente, MD, Samuel J. Rose, MD and Ellen J. Hess, MD; 11. Dystonia: Pathophysiology, Clinical Manifestations and Course Including Diagnosis, and Differential Diagnosis, Treatment, Current Clinical Trials; Jeri Yvonne Williams, MD and David G. Standaert, MD, PhD; 12. Paroxysmal Dyskinesias; Olga Waln, MD and Joseph Jankovic, MD.; 13. The Expanded Polyglutamine Tract Spinocerebellar Ataxias; Elsdon Storey, MD; 14. Ataxias: Autosomal Recessive and other Ataxias; Vikram G. Shakkottai, MD, PhD; SECTION II: Dementias (David Knopman, Mayo Clinic); 15. Alzheimer’s Disease: Pathology and Pathogenesis; Bradley T Hyman, MD, Beatriz G Perez-Nievas, MD, Isabel Barroeta-Espar, MD, Alberto Serrano-Pozo, MD, Matthew Frosch, MD, and Teresa Gomez-Isla, MD; 16. Alzheimer’s Disease: Clinical Manifestations and Diagnostic/Differential Diagnosis; Michael S. Rafii, MD, PhD; 17. Alzheimer’s Disease: Management and Treatment; Gregory A. Jicha, MD, PhD and Frederick A. Schmitt, PhD; 18. Frontotemporal Degenerations; Jonathan Graff-Radford, MD, and Keith A. Josephs, MD, MST, MSc; 19. Diagnosis and Therapy for Lewy Body Dementia; Bela R. Turk, MD and Ali Fatemi, MD; 20. Pathogenesis of Lewy Body Dementia; Jagan A. Pillai, MD, PhD and James B. Leverenz, MD; 21. Cerebrovascular Dementia; Rahul Karamchandani, MD and Nancy R. Barbas, MD, MSW; SECTION III: Motorneuron Diseases (Merit Cudkowicz, Massachusetts General Hospital, Harvard University); 22. Types of MNDS; Nimish Thakore, MD and Erik P. Pioro, MD, PhD; 23. Clinical Presentations, Diagnostic Criteria, Lab Testing; Nimish Thakore, MD and Erik P. Pioro, MD, PhD; 24. Symptomatic Care; Matthew Gladman, MD and Lorne Zinman, MD, MSc; 25. ALS: Epidemiology; Eilis J. O’Reilly, ScD; 26. ALS: Pathogenesis; Laura Ferraiuolo, MD and Stephen J. Kolb, MD; 27. ALS: Insights from Genetics; Matthew B. Harms, MD and Timothy M. Miller, MD, PhD; 28. ALS: In Vitro and In Vivo Disease Models; Brian J. Wainger, MD, PhD; 29. ALS Pathology; Brent T. Harris, MD, PhD, Galam A. Khan, MD, and Saed Sadeghi, MD; 30. ALS: Clinical Trials Past Reflections Informing New Directions; Katharine A. Nicholson, MD and James D. Berry, MD; 31. Upper Motor Neuron Disorders: Hereditary Spastic Paraplegia and Primary Lateral Sclerosis; John K. Fink, MD; 32. UMN Disorders (HSP and PLS): Pathogenesis, Insights from Genetics, In Vitro and In Vivo Disease Models, Pathology and Clinical Trials; Sabrina Paganoni, MD, PhD and Nazem Atassi, MD, MMSc; 33. SMA: Pathogenesis; Umrao R. Monani, PhD and Darryl C. De Vivo, MD; 34. SMA: Insights from Genetics; Arthur H.M. Burghes, MD and Vicki L. McGovern, MD; 35. SMA: In Vitro and In Vivo Models of Spinal Muscular Atrophy; W. David Arnold, MD and Arthur H.M. Burghes, MD; SECTION IV: Paroxysmal Disorders (Solomon Moshe, Albert Einstein College of Medicine); 36. Biological Basis of Primary Generalized Epilepsies-Genetics; Carla Marini, MD and Renzo Guerrini, MD; 37. Biological Basis of Primary Generalized Epilepsies - Pathophysiology; Mark W. Youngblood, MD and Hal Blumenfeld, MD; 38. Temporal Lobe Epilepsy; Edward H. Bertram, MD; 39. Focal Cortical Dysplasias; Ali Mahta, MD and Peter B. Crino, MD, PhD; 40. Biological Bases of Symptomatic Generalized Epilepsies in Children; Dragos A. Nita, MD, Miguel A. Cortez, MD, Jose Luis Perez Velazquez, MD, and O. Carter Snead 3rd, MD; 41. Epilepsies that Occur Predominantly in Girls; Lynette G Sadleir, MD, Jozef Gecz, MD, and Ingrid E Scheffer, MD; 42. Epidemiology of Epilepsy: Incidence, Prevalence, and Risk Factors; Dale C Hesdorffer, PhD, MPH; 43. Clinical Presentation, Diagnosis, and Course- Epilepsy Syndromes with Focal Seizures; Alex Boro, MD and Jerome Engel, Jr., MD; 44. Medical Management of Epilepsy; Jules C. Beal, MD and Emilio Perucca, MD; 45. Neuroimaging in Epilepsy; William A. Gomes, MD, PhD; 47. Alternative Therapies for Epilepsy: Dietary Treatments; Carl E. Stafstrom, MD, PhD; 48. Migraine and Other Headache Disorders; Robert W. Charlson, MD and Matthew S. Robbins, MD; 49. Neurobiology of Migraine; Victor Rosenfeld, MD and John Stern, MD; SECTION V: Pediatric Neurology and Developmental Disorders (Tanjala Gipson and Deepa Menon, Kennedy Krieger Institute and Johns Hopkins University); 50. Autism and Intellectual Disabilities: Overview of Autism and Intellectual Disabilities; Tanjala T. Gipson, MD and Michael V. Johnston, MD; 51. Tuberous Sclerosis Complex: Pediatric Aspects; Tanjala T. Gipson, MD, Andrea Poretti, MD, Rebecca McClellan, MGC, CGC, and Michael V. Johnston, MD; 52. Neurofibromatosis Type 1; David S. Wolf, MD, PhD; 53. Neurobiology of Autism and Intellectual Disability: Fragile X Syndrome; Dejan B. Budimirovic, MD and Megha Subramanian, BA; 54. Autism and Intellectual Disabilities: PTEN Gene mutation; Deepa U. Menon, MBBS, MD; 55. Rett Syndrome; C.L. Smith-Hicks, MD and SakkuBai Naidu, MD; 56. Angelman Syndrome; Kristin W. Baranano, MD, PhD; 57. Down Syndrome; George T. Capone, MD; 58. Coffin-Lowry Syndrome; Michael V. Johnston, MD; 59. Congenital Hypothyroidism; Mary Lee Gregory, MD, PhD; 60. Pediatric Neurotransmitter Disorders; Phillip L. Pearl, MD and William P. Welch, MD; 61. Attention Deficit-Hyperactivity Disorder; Mihee J. Bay, MD and Bruce K. Shapiro, MD; 62. Diseases of Mitochondrial Energy Metabolism; Jacqueline Weissman, MD, MS and Lisa Emrick, MD; 63. Genetic Metabolic Disorders: MethylmalonicAciduria; Siddharth Srivastava, MD and Jeffrey Chinsky, MD PhD; 64. The Urea Cycle Disorders; Andrea L. Gropman, MD, Belen Pappa, MD, and Nicholas Ah Mew, MD; 65. Phenylketonuria; Hilary Vernon, MD, PhD; 66. Cerebral Creatine Deficiency Disorders; Peter W. Schutz, MD and Sylvia Stockler, MD; 67. Congenial Disorders of Glycosylation; Marc C. Patterson, MD, FRACP; 68. Glutaric Aciduria Type I; Hilary Vernon, MD, PhD; 69. Lysosomal Storage Disroders; Gustavo H.B. Maegawa, MD, PhD, FACMG; 70. Peroxisomal Disorders; Gerald V. Raymond, MD, Mohamed Y. Jefri, MD, Kristin W. Baranano, MD, and Ali Fatemi, MD; 71. Leukodystrophies; Ulrike Schrifl, MD, SakkuBai Naidu, MD, and Ali Fatemi, MD; 72. Cerebral Palsy; Joan M. Jasien, MD, Bruce K. Shapiro, MD and Alexander H. Hoon, Jr., MD; 73. Neonatal Brain Injuries; Katharina Goeral, MD, Ali Fatemi, MD, and Michael V. Johnston, MD; 74. The Neurobiology of Encephalopathy of Prematurity; Gwendolyn J. Gerner, MD and Vera Joanna Burton, MD; 75. Epilepsy Syndromes in Childhood; Verena Staedtke, MD and Eric H. Kossoff, MD; 76. Migraine and Headaches in Children; Jessica Klein, MD and Christopher Oakley, MD; 77. Congenital Hydrocephalus; Vera Joanna Burton, MD and Edward Ahn, MD; 78. Spina Bifida and Related Conditions; Stephen L. Kinsman, MD; 79. Smith-Lemli-Opitz Syndrome; Ryan W. Lee, MD; 80. Sickle Cell Anemia; Eboni I. Lance, MD; SECTION VI: Neuroimmunological Diseases (Carlos Pardo-Villamizar, Johns Hopkins University); 81. The Epidemiology of Multiple Sclerosis: An Historical Perspective; Kassandra L. Munger, ScD; 82. Multiple Sclerosis: Pathology; Bogdan Florin Gh. Popescu, MD, Yong Guo, MD, and Claudia Francesca Lucchinetti, MD; 83. Multiple Sclerosis: MRI and Other Imaging Approaches in MS; Martina Absinta, MD and Daniel S. Reich, MD, PhD; 84. Multiple Sclerosis: White Matter vs Grey Matter Involvment (The Cause of Disability in MS); Massimo Filippi, MD, and Maria A. Rocca, MD.; 85. Multiple Sclerosis: Monitoring disease activity and progression; Pavan Bhargava, MD and Shiv Saidha, MBBCh, MD, MRCPI; 86. Symptomatic Treatment of Multiple Sclerosis; Kathleen Costello, RN, BSN, MS; 87. Exercise and Multiple Sclerosis; Jeffrey R Hebert, PT, PhD; 88. Multiple Sclerosis: Disease Modifying Therapies; Pavan Bhargava, MD and Peter A. Calabresi, MD; 89. Neuromyelitis Optica; Teri L. Schreiner, MD, MPH and Jeffrey L. Bennett, MD, PhD; 90. Acute Disseminated Encephalomyelitis; Benjamin M. Greenberg, MD, MHS and Allen Desena, MD; 93. Paraneoplastic Neurological Disorders; John C. Probasco, MD; 94. Anti-N-Methyl-D-Aspartate Receptor (NMDAR) Encephalitis; Elizabeth M. Wells, MD, MHS; 95. Other Proven and Putative Autoimmune Disorders of the CNS: Anti-GAD Associated Neurological Disorders; Stiff-Person syndrome, Cerebellar Ataxia, Progressive Encephalopathy with Rigidity and Myoclonus (PERM), and Encephalitis.; Scott D. Newsome, DO; 96. Other Proven and Putative Autoimmune Disorders of the CNS: Hashimoto’s Encephalopathy; Eoin P. Flanagan, MBBCh and Richard J. Caselli, MD; 97. Other Proven and Putative Autoimmune Disorders of the CNS: Neuro-Bechet’s Syndrome; Afshin Borhani Haghighi M.D and Bernadette Kalman, MD, PhD, DSc; 98. Post-Streptococcal Movement Disorders; Davide Martino, MD and Gavin Giovannoni, MD; 99. Rasmussen Encephalitis; Jan Bauer, MD and Christian G. Bien, MD; 100. Autoimmune Encephalitis; Andrew McKeon, MD; 101. Other Proven and Putative Autoimmune Disorders of the PNS: Myasthenia gravis; Doris G. Leung, MD; 102. Vasculitis of the central nervous system; Christian Pagnoux, MD and Richard H. Swartz, MD; SECTION VII: Cerebrovascular Diseases (Harold Adams, University of Iowa); 103. Stroke Epidemiology and Impact: Mortality, Incidence, Prevalence, Stroke Subtypes, Sex, Race/Ethnicity, Geography U.S. and World; Virginia J Howard, PhD; 104. Acute Ischemic Stroke; Harold P. Adams, Jr., MD; 105. Neuroimaging of Acute Stroke; Chelsea S. Kidwell, MD and Kambiz Nael, MD; 106. Common Risk Factors and Medical Prevention Therapies; George Khouri, MD, Shelly Ozark, MD, and Bruce Ovbiagele, MD, MSc, MAS; 107. Surgical and Radiologic Intervention for Prevention of Ischemic Stroke; Andrew Ringer, MD; 108. Unusual Causes of Stroke; Enrique C. Leira, MD, MS; 109. Pediatric Stroke; Melissa Chung, MD and Warren Lo, MD; 110. Vascular Biology of Cerebral Ischemia; Jason A. Ellis, MD and E. Sander Connolly, Jr., MD; 111. Intracerebral Hemorrhage; Craig Anderson, MD; 112. Subarachnoid Hemorrhage; David Hasan, MD; 113. Genetics of Cerebral Ischemia including Genetic Syndromes; Andrea Porretti, MD and Michael V. Johnston, MD; 114. Molecular Targets of Cerebral Ischemia; Ryan J. Felling, MD, PhD; 115. Sturge-Weber Syndrome and related Cerebrovascular Malformation Syndromes.; Angela Quain, MS and Anne M. Comi, MD; SECTION VIII: Peripheral and Autonomic Nervous System Disorders and Pain (Nicholas Maragakis, Johns Hopkins University); 116. Neuropathies Associated with Infection or Toxic Exposure; Doris Leung, MD; 117. Mechanisms Contributing to the Development and Progression of Diabetic Polyneuropathy; Lucy M. Hinder, PhD, Kelli A. Sullivan, PhD, Stacey A. Sakowski, PhD, and Eva L. Feldman, MD, PhD; 118. Diabetic and PreDiabetic Neuropathy; Lindsay Zilliox, MD and James W. Russell, MD, MS, FRCP; 119. Anatomy, Localization, and Pattern Recognition of Peripheral Neuropathy; Noah Kolb, MD and A. Gordon Smith, MD; 120. Drug Discovery of Neuropathic Pain; Brian J. Wainger, MD, PhD; 121. Neuropathies, Autonomic; Phillip A. Low, MD; 122. Animal Models of Peripheral Neuropathy and Neuropathic Pain; Katelyn Donaldson, MD and Ahmet Hoke, MD, PhD; 123. Diagnostic Tests and Clinical Scales for Peripheral Neuropathy; John D. Markman, MD; 124. Complex Regional Pain Syndrome; Frank S. Pidcock, MD; 125. Entrapment Neuropathies; James W. Teener, MD; 126. Demyelinating Neuropathies; John A. Goodfellow, MD, Amy I. Davidson, MD, and Hugh J. Willison, MD; 127. Immune Mediated Neuropathies; John A. Goodfellow, MD, Amy I. Davidson, MD, and Hugh J. Willison, MD; 128. Radiculopathy and Plexopathy; Michael Wheaton, MD, Dustin Nowacek, MD, and Zachary London, MD; SECTION IX: Neoplastic and Paraneoplastic Diseases (Lisa DeAngelis, Memorial Slaon-Kettering Cancer Center); 129. Infiltrative Astrocytomas: WHO grade II - Diffuse Astrocytoma; WHO grade III - Anaplastic Astrocytoma; Aaron Mammoser, MD, MS; 130. Glioblastomas; Aaron Mammoser, MD, MS; 131. Oligodendrogliomas; Thomas J. Kaley, MD; 132. Primary CNS Tumores: Ependymomas; Brett J. Theeler, MD and Mark R. Gilbert, MD; 133. Meningiomas; Jennie Taylor, MD and Patrick Y. Wen, MD; 134. Pineal Region Neoplasms; Neil Haranhalli, MD and Jerome J. Graber, MD, MPH; 135. Pituitary Tumors; Toral R. Patel, MD and Viviane S. Tabar, MD; 136. Primary Central Nervous System Lymphoma; Lisa M. DeAngelis, MD; 137. Familial CNS Tumor Syndromes: Neurofibromatosis Type 1; Ibrahim Hussain, BA and David H. Gutmann, MD, PhD; 138. Familial CNS Tumor Syndromes: Neurofibromatosis Type-2; Jennie W. Taylor, MD and Scott R. Plotkin, MD, PhD; 139. Familial CNS Tumor Syndromes: Tuberous Sclerosis; Darcy A. Krueger, MD, PhD; 140. Familial CNS Tumor Syndromes: Von Hippel-Lindau Disease; Gurvinder Kaur, MD, Leonel Ampie, MD, Joseph Weiner, MD, and Aruna Ganju, MD; 141. Pediatric Tumors: Pontine Glioma; Kristin Schroeder, MD, MPH and Oren Becher, MD; 142. Pediatric Tumors: Medulloblastoma; Kevin C De Braganca, MD and Roger J. Packer, MD; 143. Pediatric Tumors: Cerebellar Astrocytoma; Vijay Ramaswamy, MD, FRCPC, Jason T. Huse, MD, PhD, and Yasmin Khakoo, MD; 144. Brain Metastases; Jasmin Jo, MD and David Schiff, MD; 145. Overview: Other Proven and Putative Autoimmune Disorders of the CNS; Myrna R. Rosenfeld, MD, PhD, Maarten J. Titulaer, MD, PhD, and Josep Dalmau, MD, PhD; 146. Chemotherapy and Radiation Therapy; Mary R. Welch, MD and Craig Nolan, MD; SECTION X: Infectious Diseases of the Nervous System (Karen Roos, Indiana University); 147. Acute Bacterial Meningitis; Pratibha Singhi, MD, PhD, Naveen Sankhyan, MD, PhD, and Sunit Singhi, MD, PhD; 148. Cerebrospinal Fluid; John E. Greenlee, MD; 149. History of Human Immunodeficiency Virus Infection and the Nervous System; Avindra Nath, MD; 150. HIV-Associated Neurocognitive Disorders; Joshua Alexander, DO, MPH, David J Croteau, MD, FRCPC, and Ronald J Ellis, MD, PhD; 151. HIV Infection: Opportunistic Infections in HIV-Infected Individuals; William Tyor, MD; 152. Varicella Zoster Virus Infection of the Nervous System; Don Gilden, MD, Randall J. Cohrs, PhD, Ravi Mahalingam, PhD, and Maria A. Nagel, MD; 153. Brain Abcess; Bela R. Turk, MD, Ali Fatemi, MD, and Michael V. Johnston, MD; 154. Epidural Abscess and Sudural Empyema; Tyler R West, DO and Kelly J Baldwin, MD; 155. Spinal Epidural Abcess; Minal A. Shah, MD and Rabih O. Darouiche, MD; 156. Transverse Myelitis; Ivana Vodopivec, MD, PhD and Tracey A. Cho, MD; 157. CNS Tuberculosis; Andrea T. Cruz, MD, MPH, and Jeffrey R. Starke, MD; 158. Rabies; Alan C. Jackson, MD; 159. Disorders Caused by Botulinum Toxin and Tetanus Toxin; Carl E. Stafstrom, MD, PhD; 160. Rickettsial Diseases; Lisa Sun, MD and Michael V. Johnston, MD; 161. Ehrlichial Diseases; Nicholas S. Havens, MD and William E. Roland, MD, FACP; 162. Nervous System Lyme Disease; John J. Halperin, MD; 163. Congenital and Perinatal Viral Infections; James F. Bale, Jr., MD; 164. Neurologic Manifestations of HTLV-1; Abelardo Q-C Araujo, MD, MSc, PhD, FAAN; 165. Fungal Infections of the Central Nervous System; Pratibha Singhi,MD, Karthi Nallasamy, MD, and Sunit Singhi, MD; 166. Malaria; Kiran Thakur, MD; 167. Babesiosis; Kristyn E. Feldman, MD and Joshua Biddle, MD; 168. Amebic Encephalitis; Pratibha Singhi, MD and Arushi G. Saini, MD; 169. Prions; James A. Mastrianni, MD, PhD and Joshuae G. Gallardo, MD; 170. Neurological Complications of Infective Endocarditis; Jonah Grossman, MD, Tanzila Shams, MD, and Cathy Sila, MD; 171. Post-Infectious Encephalitis; Agusto A. Miravalle, MD; 172. Central Nervous System Whipple Disease; Arun Venkatesan, MD, PhD; 173. Progressive Multifocal Leukoencephalopathy; Arun Swaminathan, MBBS and Joseph R. Berger, MD; SECTION XI: Sleep Disturbances (Mark Dyken, University of Iowa); 174. REM Sleep Behavior Disorder; Shannon S. Sullivan, MD; 175. Restless Leg Syndrome and Periodic Limb Movements in Sleep; Jennifer Accardo, MD, MSCE; 176. Insomnia; Wilfred R. Pigeon, MD and Henry J. Orff, MD; 177. Sleep Apnea; Jennifer Accardo, MD, MSCE; 178. Neurobiology of Circadian Rhythm Disorders; Christopher R. Jones, MD, PhD; SECTION XII: Substance Abuse and Toxicological Disorders (Barry Kosofsky, Weil-Cornell University Medical Centers); 179. Neurologic Manifestations of Organic Chemicals; John L. O’Donoghue, VMD, PhD, DABT; 180. Neurobiology of Drug Addiction and Clinical Aspects of Drug Abuse; Leslie R. Whitaker, MD and Bruce T. Hope, MD; 181. Neurological Effects of Marine Toxins; Kazuma Nakagawa, MD; 182. Fetal Alcohol Syndrome; Carmen Lopez-Arvizu, MD, Carmel Bogle, MD, and Harolyn M.E. Belcher, MD, MHS; 183. Fetal Exposure to Tobacco and Cannabis; Edore C. Onigu-Otite, MD; 184. Neurobiology of Child Maltreatment and Psychological Trauma; Nikeea Copeland-Linder, PhD, MPH, Edore Onigu-Otite, MD, Jennifer Serico, PhD, Mariflor Jamora, MD, and Harolyn M.E. Belcher, MD, MHS; 185. Neurobiology of Intrauterine Opiate and Cocaine Exposure; Harolyn M.E. Belcher, MD, MHS and Samantha Hutchison, MD; SECTION XIII: Neurologic Manifestations of Medical Disorders (John Probasco, Johns Hopkins University); 186. Electrolyte Disturbances; Mark N. Rubin, MD and Alejandro A. Rabinstein, MD; 187. Nutritional Deficiencies; Deanna Saylor, MD, MHS and John C. Probasco, MD; 188. Alcohol Abuse; Killian A. Welch, MD; 189. Thyroid Disease; Makoto Ishii, MD, PhD; 190. Parathyroid, Adrenal, Ovarian, Testicular and Pituitary Disease; Gary M. Abrams, MD; 191. Cardiac Disease; Roger E. Kelley, MD; 192. Neurobiology of Brain Injury after Cardiac Arrest; Lucia Rivera-Lara, MD and Romergryko G. Geocadin, MD; 193. Gastrointestinal Disease; Brian P. Bosworth, MD, Brian R. Landzberg, MD, and Elisa McEachern, MD; 194. Neurological Manifestations of Renal Disease; Joshua S. Hundert, MD, Rashmi Verma, MD, Ritika Suri, MD, Anika T. Singh, MD, and Ajay Singh, MD; 195. Systemic Lupus Erythematosis; Richard B. Rosenbaum, MD; 196. Neurologic Manifestations of Hematological Disease; Elham Bayat, MD

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