Oxidative Eustress in Exercise Physiology(Oxidative Stress and Disease)

运动生理学中的氧化应激

生物化学

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出  版 社
出版时间
2022年04月05日
装      帧
精装
ISBN
9780367508760
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页      码
240
开      本
254 x 178 mm (7 x 10)
语      种
英文
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图书简介
This book unravels key physiological responses and adaptations to different redox regulated exercise paradigms at the cell, tissue, and whole-body level in model systems and humans in health and disease. While the mechanistic details are still unclear, key intracellular redox indices seem to be dysregulated with age. Consequently, beneficial molecular responses to acute endurance exercise decline in older individuals. Recent research suggests that manipulating mitochondrial redox homeostasis by supplementing with the mitochondria targeted co-enzyme Q10 for six weeks markedly improves physical function in older adults; i.e. it may be possible to maximize the benefits of exercise by manipulating the redox environment. The research described in this book suggests that significant translational potential exists with respect to cardiovascular disease, neurodegeneration, and cancer. An international team of researchers document the importance of redox biology in health and disease; especially when exercise is a clinically useful tool for the treatment of many diseases and conditions.Key FeaturesDefines essential redox biology reactions and concepts in exercise physiology.Assesses key redox parameters in an in vivo human exercise context.Identifies the challenges, opportunities, and boundaries of current knowledge.Includes a critique the underlying mechanisms.Summarizes examples of translationally important research relating to disease states.
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