图书简介
This book examines applications of multi-omics approaches for understanding disease etiology, pathogenesis, host-pathogen interactions. It also analyzes the genetics, immunological and metabolic mechanisms underlying the infections. The book also explores genomics, transcriptomics, translational-omics, and metabolomics approaches to understand the pathogenesis and identify potential drug targets. It reviews the role of epigenetic reprogramming in shaping the host-pathogen interactions and presents bioinformatics application in the identification of drug targets. Further, it examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current challenges, technological advances, and prospects of using multi-omics technologies in infectious biology.
Chapter 1. Geno-Informatics for Prediction of Virulence and Drug Resistance in Bacterial Pathogens.- Chapter 2. Next Generation Sequencing: Challenges and Opportunities in Tuberculosis Research.- Chapter 3. Deciphering the role of epigenetic reprogramming in host-pathogen interactions.- Chapter 4. Genomic evidence provides the understanding of SARS-CoV-2 composition, divergence and diagnosis.- Chapter 5. Importance of Next Generation Sequencing in Viral Diagnostics.- Chapter 6. Bioinformatics application in CoVID19.- Chapter 7. Emerging Transcriptomics approaches to decipher Mycobacterial complexities.- Chapter 8. Microarrays: A road map to uncover host pathogen interactions.- Chapter 9. Transcriptional Approach in the Identification of Drug Targets in Candida spp.- Chapter 10. Non-Coding RNA profiling: Potential Application in Infectious Diseases.- Chapter 11. RNA-seq analysis strategies to understand viral pathogenesis.- Chapter 12. Various Transcriptomic approaches
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