图书简介
Flow Cytometry of Hematological Malignancies contains an array of graphical outputs produced by the technique in the study of the most (and the least) common diseases. The images included allow you to compare your own results with a third party reference pattern. There is a detailed description of the main leukocyte antigens, together with a description of their distribution amongst normal and abnormal blood cells. The book also provides a comprehensive description of the phenotype of every neoplastic blood disease recorded in the WHO classification system, including all the instructions needed to recognise and classify even the least common entity. Designed to be practical, the book is perfect for quick consultation and is divided into two main sections. Section I deals with the direct object of immunophenotyping, and Section II deals with the ultimate target of the analysis. More than 50 antigens are covered and every antigen is dealt with in three main parts: general features, cytometric features and practical hints. This authoritative and state-of-the-art reference will be invaluable for clinicians directly involved in the diagnosis and analysis of hematological diseases, including hematologists, hematopathologists, oncologists, pathologists and technicians working in diagnostic laboratories.
Foreword to the First Edition by Maryalice Stetler-Stevenson Foreword to the First Edition by Bruno Brando Foreword to the Second Edition by Michael J Borowitz Preface to the First Edition Preface to the Second Edition 1 ANTIGENS Clustered (CD) Antigens CD1 Antigens, XX CD2 Antigen, XX CD3 Antigen, XX CD4 Antigen, XX CD5 Antigen, XX CD7 Antigen, XX CD8 Antigen, XX CD10 Antigen, XX CD11b Antigen, XX CD11c Antigen, XX CD13 Antigen, XX CD14 Antigen, XX CD15 Antigen, XX CD16 Antigen, XX CD19 Antigen, XX CD20 Antigen, XX CD22 Antigen, XX CD23 Antigen, XX CD24 Antigen, XX CD25 Antigen, XX CD26 Antigen, XX CD27 Antigen, XX CD28 Antigen, XX CD30 Antigen, XX CD33 Antigen, XX CD34 Antigen, XX CD38 Antigen, XX CD43 Antigen, XX CD45 Antigen, XX CD45 Isoforms, XX CD48 Antigen, see SLAM molecules, XX CD49 Antigens, XX CD56 Antigen, XX CD57 Antigen, XX CD61 Antigen, XX CD62L Antigen, XX CD64 Antigen, XX CD65 Antigen, XX CD66c Antigen, XX CD71 Antigen, XX CD79 Antigen, XX CD81 Antigen, XX CD84 Antigen, see SLAM molecules, XX CD103 Antigen, XX CD123 Antigen, XX CD117 Antigen, XX CD138 Antigen, XX CD150 Antigen, see SLAM molecules, XX CD158 Antigen, see KIRs, XX CD181-186, 191-199 Antigens, see Chemokines and Chemokine Receptors, XX CD200 Antigen, XX CD229 Antigen, see SLAM molecules, XX CD244 Antigen, see SLAM molecules, XX CD280-290 Antigens, see Toll-like Receptors, XX CD305 Antigen, XX CD307 (IRTA) Antigen Family, XX CD319 Antigen, see SLAM molecules, XX CD352-353 Antigens, see SLAM molecules, XX CD371 Antigen, XX Non clustered (or primarily known with other names) antigens Bcl-2 Protein, XX Chemokines and Chemokine Receptors, XX CRLF2, XX Cytotoxic Proteins, XX HLA-DR Antigen, XX Immunoglobulins, XX KIR, CD158 Isoforms, XX Myeloperoxidase (MPO), XX NG2 Antigen, XX PCA-1 Antigen, XX ROR-1 Antigen, XX SLAM Molecules and SLAM Associated Protein (SAP), XX SOX11, XX T-cell Receptor (TCR), XX Terminal Deoxy-nucleotidyl Transferase (TdT), XX Toll-like Receptors (TLR), XX VS38 Antigen, XX ZAP-70 Protein, XX 2 DISEASES Myeloproliferative neoplasms, XXX Chronic myeloid leukemia (CML), XXX Myeloproliferative neoplasms other than CML, XXX Chronic neutrophilic leukemia (CNL), XXX Polycythemia vera (PV), XXX Primary myelofibrosis (PMF), XXX Essential thrombocythemia (ET), XXX Chronic eosinophilic leukemia (CEL), XXX Mastocytosis, XXX Acute masT-cell leukemia (AMCL), XXX Chronic masT-cell leukemia (CMCL), XXX Myelomastocytic leukemia (MML), XXX Myelodysplastic/myeloproliferative neoplasms, XXX Chronic myelomonocytic leukemia (CMML), XXX Other myelodysplastic/myeloproliferative neoplasms and related conditions, XXX Juvenile myelomonocytic leukemia (JMML), XXX Atypical CML bcr/abl negative (ACML), XXX RAS-associated autoimmune leukoproliferative disorder (RALD), XXX Myelodysplastic syndromes, XXX Myeloid neoplasms with germline predisposition, XXX Acute myeloid leukemias, XXX AMLs with recurrent genetic anomalies, XXX AMLs with chromosomal anomalies, XXX AMLs with gene mutations, XXX AMLs with recurrent genetic anomalies, not recognized by the WHO classification, XXX AMLs with myelodysplastic related changes (AML-MRC), XXX AMLs not otherwise specified, XXX AML with minimal differentiation, XXX AML without maturation, XXX AML with maturation, XXX Acute myelomonocytic leukemia (AMMoL), XXX Acute monoblastic or monocytic leukemia (AMoL), XXX Pure erythroid leukemia (PEL), XXX Acute megakaryoblastic leukemia (AMKL), XXX Acute basophilic leukemia (ABL), XXX Myeloid proliferations associated with Down syndrome, XXX Transient abnormal myelopoiesis (TAM), XXX AMLs in patients with Down syndrome, XXX Blastic plasmacytoid dendritic cell neoplasm (BPDCN/PDCL), XXX Acute leukemias with ambiguous lineage attribution (ALAL), XXX Acute undifferentiated leukemias (AUL), XXX Mixed phenotype acute leukemias (MPAL), XXX Neoplastic diseases of B and T lymphatic precursors, XXX B lymphoblastic leukemia/lymphoma, not otherwise specified (B-ALL/LBLnos), XXX B lymphoblastic leukemia/lymphoma with recurrent genetic anomalies, XXX T lymphoblastic leukemia/lymphoma (T-ALL/LBL), XXX Early T-cell precursors lymphoblastic leukemia (ETP-ALL), XXX NK lymphoblastic leukemia/lymphoma (NK-ALL/LBL), XXX Neoplastic diseases of mature B cells, XXX Chronic lymphocytic leukemia/small lymphocytic lymphoma (B-CLL/SLL), XXX Familial B-CLL, XXX Richter syndrome, XXX Monoclonal B-cell lymphocytosis (MBL), XXX B-cell prolymphocytic leukemia (B-PLL), XXX Lymphoplasmacytic lymphoma (LPL), XXX Heavy chain disease (HCD), XXX Gamma heavy chain disease, XXX Mu heavy chain disease, XXX Alpha heavy chain disease, XXX Hairy cell leukemia (HCL), XXX Hairy cell leukemia, variant (HCL-v), XXX Hairy cell leukemia, Japanese variant (HCL-J), XXX Splenic diffuse red pulp lymphoma (SDRPL), XXX Marginal zone lymphomas (MZL), XXX Nodal marginal zone lymphoma (NMZL), XXX Splenic marginal zone lymphoma (SMZL), XXX Extranodal marginal zone lymphoma (EMZL/MALToma), XXX Clonal B-cell lymphocytosis with MZL-like phenotype (CBL-MZ), XXX Follicular lymphoma (FCL), XXX Testicular follicular lymphoma, XXX Duodenal type follicular lymphoma, XXX Pediatric type follicular lymphoma, XXX Primitive cutaneous follicular lymphoma (PCFL), XXX Large B-cell lymphoma with IRF4 rearrangement, XXX Mantle cell lymphoma (MCL), XXX Blastic mantle cell lymphoma (BMCL), XXX Leukemic non nodal mantle cell lymphoma, XXX Diffuse large B-cell lymphomas (DLBCLs), XXX DLBCL not otherwise specified (DLBCL nos), XXX T-cell/histiocyte-rich B-cell lymphoma (THRLBCL), XXX Primary DLBCL of the CNS (PCNSL), XXX Primary cutaneous DLBCL, \"leg type\", XXX EBV(+) DLBCL nos, XXX DLBCL associated with chronic inflammation (PAL), XXX Lymphomatoid granulomatosis (LyG), XXX Primary mediastinal B-cell lymphoma (PMBCL), XXX Intravascular large B-cell lymphoma (IVBCL), XXX ALK-positive large cell lymphoma (ALK(+) LBCL), XXX Plasmablastic lymphoma (PBL), XXX Primary effusion lymphoma (PEL), XXX HHV8-associated lymphoproliferative disorders, XXX Burkitt lymphoma (BL), XXX Burkitt leukemia with immature phenotype, XXX Burkitt-like lymphoma with 11q aberrations, XXX High grade B-cell lymphoma (HGBL), XXX Plasma cell neoplasms, XXX Monoclonal gammopathies of undetermined significance (MGUS), XXX Multiple myeloma (MM), XXX Plasma cell leukemia (PCL), XXX Neoplastic diseases of mature T and NK cells, XXX T-cell prolymphocytic leukemia (T-PLL), XXX T-cell large granular lymphocytic leukemia (T-LGL), XXX Chronic lymphoproliferative disorders of NK cells (CLPD-NK/CNKL), XXX Aggressive NK-cell leukemia (ANKL), XXX Adult T-cell leukemia/lymphoma (ATLL), XXX Extranodal NK/T-cell lymphoma, \"nasal type\" (ENKTL), XXX Intestinal T-cell lymphoma (ITCL), XXX Enteropathy-associated T-cell lymphoma (EATCL), XXX Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL), XXX Indolent gastro-intestinal T lymphoproliferative disorder, XXX Hepatosplenic T-cell lymphoma (HTSCL), XXX Subcutaneous panniculitis-like T-cell lymphoma (SPTCL), XXX Mycosis fungoides (MF), XXX Sezary syndrome (SS), XXX Primary cutaneous CD30(+) lymphoproliferative disorders, XXX Lymphomatoid papulosis (LyP), XXX Primary cutaneous anaplastic T-cell lymphoma (cALCL), XXX Primary cutaneous peripheral T-cell lymphoma (PTCL), XXX Primary cutaneous TCR (+) T-cell lymphoma (PCGD-TCL), XXX Primary cutaneous CD8(+) aggressive epidermotropic cytotoxic T-cell lymphoma, XXX Primary cutaneous acral CD8(+) T-cell lymphoma Primary cutaneous lymphoma of the medium/small CD4(+) T cells (PCSM-TCL), XXX Peripheral T-cell lymphoma, not otherwise specified (PTCLnos), XXX Nodal lymphomas of follicular T-helper derivation, XXX Angioimmunoblastic T-cell lymphoma (AITL), XXX Follicular T-cell lymphoma (FTCL), XXX Nodal PTCL with follicular T-helper phenotype, XXX Anaplastic large cell lymphoma ALK(+) (ALK(+) ALCL), XXX Anaplastic large cell lymphoma ALK(-) (ALK(-) ALCL), XXX Breast implant-associated anaplastic large cell lymphoma (biaALCL), XXX Neoplastic diseases of histiocytic and dendritic cells, XXX Histiocytic sarcoma (HS), XXX Langerhans cell histiocytosis (LCH), XXX Indeterminate dendritic cell tumor (IDCT), XXX Interdigitating dendritic cell sarcoma (IDCS), XXX Follicular dendritic cell sarcoma (FDCS), XXX Erdheim-Chester disease (EDC), XXX 3 APPENDIX Acute leukemias not recognized by the 2016 WHO classification, XXX Acute leukemia of myeloid/NK precursors (M/NK-AL), XXX Acute leukemia of myeloid dendritic cells (MDCL), XXX Acute leukemia of Langerhans cells, XXX Mature B-cell lymphoblastic leukemia, XXX Composite lymphomas, XXX Hypereosinophilic syndrome (HES), lymphocyte variant, XXX Indolent T lymphoblastic proliferations (iT-LBP), XXX Polyclonal lymphocytoses of B lymphocytes, XXX Persistent polyclonal B-cell lymphocytosis (PPBL), XXX Persistent polyclonal CD5(+) B-cell lymphocytosis, XXX Persistent polyclonal B-cell lymphocytosis, Japanese (hairy) variant, XXX Polyclonal plasmacytoses, XXX Small round (blue) cell tumors (SR(B)CT), XXX Index
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