Pharmaceutical and Medical Applications of Near-Infrared Spectroscopy

图书简介

Now in its second edition, this volume covers the instrumentation, computerization, calibration, and methods development of NIR spectroscopy. It examines novel applications for accurate time- and cost-effective analyses of pharmaceuticals as well as biomedical applications. The book covers pharmaceutical assays, including qualitative analysis, quantitative analysis, determination of actives in tablets and capsules, and considerations for intact dosage form analysis. It also explores a range of medical applications, including those related to blood glucose measurements, tissue and major organ analysis, fetal analysis, and cancer research.

Basic principles and theory . History. Early instrumentation. Spectroscopic theory. Light-particle interaction. Instrumentation. Filter-based instruments. Scanning grating monochromators. Interferometer-based instruments. Acousto-optic tunable filters. Photodiode arrays. Specialty and custom instruments. Optical parameter instrumentation. Strengths and shortcomings of traditional types of equipment. Blend uniformity analysis. Mixing. Discussion of reported work. Sampling and data handling. Segregation, Demixing, and Particle Size. Granulation, Drying, and Coating. Monitoring Granulation and Drying. Coating and Pelletization. Pharmaceutical assays. Qualitative analysis. Quantitative analysis. Determination of actives in tablets and capsules. Considerations for intact dosage form analysis. Validation issues. International conference on harmonization. Historical perspective. Medical applications. Blood glucose. Blood oxygenation. Tissue. Major organs. Blood chemistry. Fetuses and newborns. Cancer and precancer. Photon migration in tissues. Review articles. Index .

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Pharmaceutical and Medical Applications of Near-Infrared Spectroscopy（Practical Spectroscopy） 近红外光谱药品和医疗应用 制药工程

Pharmaceutical and Medical Applications of Near-Infrared Spectroscopy（Practical Spectroscopy）

近红外光谱药品和医疗应用
制药工程