Introduction to Bioinformatics with R:A Practical Guide for Biologists(Chapman & Hall/CRC Computational Biology Series)

使用 R 的生物信息学导论:生物学家的实用指南

生物数学

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作      者
出  版 社
出版时间
2020年10月05日
装      帧
平装
ISBN
9781138495715
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页      码
284
开      本
6-1/8 x 9-1/4
语      种
英文
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图书简介
In biological research, the amount of data available to researchers has increased so much over recent years, it is becoming increasingly difficult to understand the current state of the art without some experience and understanding of data analytics and bioinformatics. An Introduction to Bioinformatics with R: A Practical Guide for Biologists leads the reader through the basics of computational analysis of data encountered in modern biological research. With no previous experience with statistics or programming required, readers will develop the ability to plan suitable analyses of biological datasets, and to use the R programming environment to perform these analyses. This is achieved through a series of case studies using R to answer research questions using molecular biology datasets. Broadly applicable statistical methods are explained, including linear and rank-based correlation, distance metrics and hierarchical clustering, hypothesis testing using linear regression, proportional hazards regression for survival data, and principal component analysis. These methods are then applied as appropriate throughout the case studies, illustrating how they can be used to answer research questions. Key Features: ·;;;;;;;; Provides a practical course in computational data analysis suitable for students or researchers with no previous exposure to computer programming. ·;;;;;;;; Describes in detail the theoretical basis for statistical analysis techniques used throughout the textbook, from basic principles ·;;;;;;;; Presents walk-throughs of data analysis tasks using R and example datasets. All R commands are presented and explained in order to enable the reader to carry out these tasks themselves. ·;;;;;;;; Uses
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