It has been several years since publication of The Biology and Treatment of Cancer (by Arthur D. Pardee and Gary Stein - Wiley-Blackwell). That book captured the fundamental properties of Cancer Biology and relevant issues associated with treatment of the disease. For this new edition, the editors are interested to include coverage of additional "patient centric" topics and for a presentation of cancer biology with selection of topics, facts, and perspectives with clarity that is maximally comprehendible without a scientific or biomedical background. Recent advances in understanding cancer have been transformative. Significant breakthroughs in the molecular and cellular basis of cancer have provided strategies for approaching cancer prevention, early detection, treatment incorporating clinical trials and recovery that "make a significant difference". The authors have been encouraged by colleagues to develop an updated edition of The Biology and Treatment of Cancer that incorporates the recently acquired insight into the genetic and epigenetic parameters of cancer biology and pathology with indications of emerging clinical applications. This updated edition will present an overview of cancer with emphasis on considerations, mechanisms and options to navigate the emerging road map from cancer prevention to early detection, treatment and recovery will be a unique and valued resource for cancer patients and caregivers. Equally important, while there are authoritative and comprehensive books focused on the mechanistic and clinical facets of cancer, this book will be important for the academic and clinical care "markets". There is a requirement for an authoritative overview and perspective of the challenges and opportunities associated with cancer biology, cancer research and the spectrum of clinical considerations that are central to "experiencing cancer" as well as to studying, investigating and treating cancer. To accommodate the requirements for a book that provides a resource for cancer patients, cancer health care providers and cancer investigators as well as supports academic requirements for broad coverage of cancer for undergraduate, graduate and medical students, Dr. Stein has partnered with his deputy director for the Vermont Cancer Center. Together, they bring experience and perspectives of a Cancer Center Director with longstanding experience in cancer research and a Cancer Center Administrator/Cancer Clinical Trials Director with a background in oncology nursing and dedication to cancer patient care. They will enlist leaders in cancer research, cancer care and clinical trials to provide accurate and balanced understanding of cancer and the cancer patient. Each chapter will be developed to illustrate the importance of cancer prevention, early detection, treatment and survivorship. Each chapter will relate the significance for a seamless continuum from cancer research to clinical trials and the translation to advancing standards of care that provide a "competitive challenge to cancer" and the emerging transition of cancer from a life threatening to a "treatable disease".

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